NBR1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A3949-20, A3949-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 107kDa
Observed Molecular Weight: 120kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 4077
SWISS: Q14596
Alternate Names: IAI3B; M17S2; MIG19; 1A1-3B; NBR1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cell Biology Developmental Biology, Autophagy, Endocrine Metabolism, Mitochondrial metabolism.
NCBI Alias: NBR1
Research Use Only