NDUV1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA33521-50, RA33521-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: NADH:ubiquinone oxidoreductase core subunit V1 (NDUFV1) Homo sapiens The mitochondrial respiratory chain provides energy to cells via oxidative phosphorylation and consists of four membrane-bound electron-transporting protein complexes (I-IV) and an ATP synthase (complex V). This gene encodes a 51 kDa subunit of the NADH:ubiquinone oxidoreductase complex I; a large complex with at least 45 nuclear and mitochondrial encoded subunits that liberates electrons from NADH and channels them to ubiquinone. This subunit carries the NADH-binding site as well as flavin mononucleotide (FMN)- and Fe-S-biding sites. Defects in complex I are a common cause of mitochondrial dysfunction; a syndrome that occurs in approximately 1 in 10, 000 live births. Mitochondrial complex I deficiency is linked to myopathies, encephalomyopathies, and neurodegenerative disorders such as Parkinson's disease and Leigh syndrome. Alternative splicing results in multiple trans Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 51 Protein Molecular Weight (kDa): 51 Storage: -20°C/1 year Human Gene ID: 4723 Human SwissProt Number: P49821 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only