NEFH Monoclonal Antibody - BT-MCA2337

NEFH Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2337-50, BT-MCA2337-100

Citations, Manuals and MSDS Available upon request.

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene.

Research Areas: Neuroscience

Target Protein: NEFH

Applications: IHC

Clonality: Monoclonal

Clone ID: 2C12F3

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NEFH

Immunogen: Purified recombinant fragment of human NEFH (AA: 2-251) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 112.4kDa

UniProt Accession: P12036

Synonyms: NFH, CMT2CC

GeneID: 4744

Research Use Only