NEFL Monoclonal Antibody - BT-MCA3752

NEFL Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3752-50, BT-MCA3752-100

Citations, Manuals and MSDS Available upon request.

Background: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

Research Areas: Neuroscience

Target Protein: NEFL

Applications: WB, IHC, ICC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 2G10

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NEFL

Immunogen: Purified recombinant fragment of human NEFL expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 62kDa

UniProt Accession: P07196

Synonyms: NFL, NF-L, NF68, CMT1F, CMT2E

GeneID: 4747

Research Use Only