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NEU1 Rabbit pAb - A6299

NEU1 Rabbit pAb - A6299

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NEU1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A6299-20, A6299-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is a lysosomal enzyme that cleaves terminal sialic acid residues from substrates such as glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (the latter is also referred to as 'protective protein') . Mutations in this gene can lead to sialidosis, a lysosomal storage disease that can be type 1 (cherry red spot-myoclonus syndrome or normosomatic type), which is late-onset, or type 2 (the dysmorphic type), which occurs at an earlier age with increased severity.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 45kDa

Observed Molecular Weight: 45kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 4758

SWISS: Q99519

Alternate Names: NEU; NANH; SIAL1; NEU1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% sodium azide, 50% glycerol, pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine Metabolism, Amino acid metabolism.

NCBI Alias: NEU1

Research Use Only