Neurofibromin Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA27719-50, RA27719-100 Citations, Manuals and MSDS Available upon request. Background: neurofibromin 1 (NF1) Homo sapiens This gene product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications. Alternative Names: NF1; Neurofibromin; Neurofibromatosis-related protein NF-1 Applications: WB; IF/ICC; ELISA Species Cross-Reactivity: Human; Mouse; Rat GeneID (Human): 4763 Protein MW (KDa): 319 SWISS: P21359 Source: Rabbit Research Use Only