Neurophysin I Polyclonal Antibody - RA27726

Neurophysin I Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27726-50, RA27726-100

Citations, Manuals and MSDS Available upon request.

Background: oxytocin/neurophysin I prepropeptide (OXT) Homo sapiens This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: OXT; OT; Oxytocin-neurophysin 1; OT-NPI

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Rat

GeneID (Human): 5020

Protein MW (KDa): 19

SWISS: P01178

Source: Rabbit

Research Use Only