Product Description

NF-E4 (Acetyl Lys43) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27753-50, RA27753-100

Citations, Manuals and MSDS Available upon request.

Background: nuclear factor, erythroid 4 (NFE4) Homo sapiens The erythroid-specific protein encoded by this gene, and the ubiquitous transcription factor CP2, form the stage selector protein (SSP) complex, which is involved in preferential expression of the gamma-globin genes in fetal erythroid cells. Alternate use of an in-frame upstream non-AUG (CUG) translation initiation codon, and a downstream AUG codon, results in two isoforms. While the long isoform (22 kDa) acts as an activator, the short isoform (14 kDa) has been shown to repress gamma-globin gene expression. This gene is located in an intron of the FBXL13 gene on the opposite strand. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: NFE4; Transcription factor NF-E4

Applications: WB; ELISA

Species Cross-Reactivity: Human; Rat; Mouse

GeneID (Human): 58160

Protein MW (KDa): 19

SWISS: Q86UQ8

Source: Rabbit

Research Use Only