Product Description

NFATc2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27746-50, RA27746-100

Citations, Manuals and MSDS Available upon request.

Background: nuclear factor of activated T-cells 2 (NFATC2) Homo sapiens This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR) . This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-200, ELISA 1:10000-20000

Alternative Names: Nuclear factor of activated T-cells, cytoplasmic 2 (NF-ATc2;NFATc2;NFAT pre-existing subunit;NF-ATp;T-cell transcription factor NFAT1)

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 4773

Protein MW (KDa): 100

SWISS: Q13469

Source: Rabbit

Research Use Only