NFKB2 Monoclonal Antibody - BT-MCA2051

NFKB2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2051-50, BT-MCA2051-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

Research Areas: Cell Biology

Target Protein: NFKB2

Reactivity: Human, Mouse

Clonality: Monoclonal

Clone ID: 5E6A12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NFKB2

Immunogen: Purified recombinant fragment of human NFKB2 (AA: 712-900) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 96.7kDa

UniProt Accession: Q00653

Synonyms: p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100

GeneID: 4791

Research Use Only