NFKBIB Monoclonal Antibody - BT-MCA2807

NFKBIB Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA2807-50, BT-MCA2807-100

Citations, Manuals and MSDS Available upon request.

Background: Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further IKBA-dependent inactivation. Association with inhibitor kappa B-interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation.Tissue specificity: Expressed in all tissues examined.

Research Areas: Signal Transduction

Target Protein: NFKBIB

Applications: WB

Reactivity: Human

Clonality: Monoclonal

Clone ID: 7B4

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NFKBIB

Immunogen: Purified recombinant fragment of human NFKBIB expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 45kDa

UniProt Accession: Q15653

Synonyms: IKBB, TRIP9, NFKBIB

GeneID: 4793

Research Use Only