NKX2-5 Rabbit pAb - A5651

NKX2-5 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5651-20, A5651-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 35kDa

Observed Molecular Weight: 37kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 1482

SWISS: P52952

Alternate Names: CSX; CSX1; VSD3; CHNG5; HLHS2; NKX2E; NKX2.5; NKX4-1; NKX2-5

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cell Biology Developmental Biology, Neuroscience, Stem Cells, Mesenchymal Stem Cells, Cardiovascular, Heart, Cardiogenesis.

NCBI Alias: NKX2-5

Research Use Only