NMDAε3 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA27877-50, RA27877-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: glutamate ionotropic receptor NMDA type subunit 2C (GRIN2C) Homo sapiens This gene encodes a subunit of the N-methyl-D-aspartate (NMDA) receptor, which is a subtype of ionotropic glutamate receptor. NMDA receptors are found in the central nervous system, are permeable to cations and have an important role in physiological processes such as learning, memory, and synaptic development. The receptor is a tetramer of different subunits (typically heterodimer of subunit 1 with one or more of subunits 2A-D), forming a channel that is permeable to calcium, potassium, and sodium, and whose properties are determined by subunit composition. Alterations in the subunit composition of the receptor are associated with pathophysiological conditions such as Parkinson's disease, Alzheimer's disease, depression, and schizophrenia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: IHC-p, IF (paraffin section), ELISA Alternate Names: GRIN2C, NMDAR2C, Glutamate [NMDA] receptor subunit epsilon-3, N-methyl D-aspartate receptor subtype 2C, NMDAR2C, NR2C Clonality: Polyclonal Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications. Storage: -20°C/1 year Human Gene ID: 2905 Human SwissProt Number: Q14957 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only