Product Description

NMRL1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES14475-50, ES14475-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human NMRL1 AA range: 179-229

Isotype: IgG

Target: NMRL1

Specificity: This antibody detects endogenous levels of NMRL1 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 33kD

Function: Similarity: Belongs to the NmrA-type oxidoreductase family
Subunit: Homodimer, disulfide-linked

Subcellular Location: Cytoplasm Cytoplasm, perinuclear region Nucleus Under normal redox growth conditions localizes in the cytoplasm and perinuclear region Nuclear localization is promoted by increased intracellular nitric oxide and reduced NADPH/NADP(+) ratios

Storage and Stability: -20°C/1 year

Gene Name: NMRAL1 HSCARG

Protein Name: NMRL1

Mouse Gene ID: 67824

Mouse SwissProt Number: Q8K2T1

Rat SwissProt Number: P86172

Research Use Only