Product Description

NOVA2 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES14466-50, ES14466-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human NOVA2 AA range: 274-324

Isotype: IgG

Target: NOVA2

Specificity: This antibody detects endogenous levels of NOVA2 at Human

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Brain, Expression restricted to astrocytes,

Molecular Weight (Da): 54kD

Function: Disease: Autoantigen in the paraneoplastic opsoclonus myoclonus ataxia (POMA), a paraneoplastic neurological syndrome/disorder (PNS/D) associated with breast cancer, fallopian cancer, and SCLCa and characterized primarily by loss of inhibitory control of motor neurons in the spinal cord and brainstem. Recognized by the IgG autoantibody ANNA-2 (also called anti-Ri)
Domain: The third KH domain (KH3) recognizes specifically 5'-UCAY-3'
Function: May regulate RNA splicing or metabolism in a specific subset of developing neurons (By similarity). Binds single strand RNA
Similarity: Contains 3 KH domains
Subunit: Interacts with PTBP2
Tissue Specificity: Brain. Expression restricted to astrocytes

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: NOVA2 ANOVA NOVA3

Protein Name: NOVA2

Research Use Only