Product Description

NPL4 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33608-50, RA33608-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: domain:Binds ubiquitinated proteins via its RanBP2-type zinc finger., function:The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope., pathway:Protein degradation; proteasomal ubiquitin-dependent pathway., similarity:Belongs to the NPL4 family., similarity:Contains 1 RanBP2-type zinc finger., subcellular location:Associated with the endoplasmic reticulum and nuclear., subunit:Heterodimer with UFD1L. The heterodimer binds ubiquitinated proteins. The heterodimer binds to VCP and inhibits Golgi membrane fusion., tissue specificity:Expressed at highest levels in brain, heart, skeletal muscle, kidney and fetal liver.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 66

Protein Molecular Weight (kDa): 66

Storage: -20°C/1 year

Human Gene ID: 55666

Human SwissProt Number: Q8TAT6

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only