NPM1 Rabbit pAb - A17983

NPM1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A17983-20, A17983-100

Citations, Manuals and MSDS Available upon request.

Background: The protein encoded by this gene is involved in several cellular processes, including centrosome duplication, protein chaperoning, and cell proliferation. The encoded phosphoprotein shuttles between the nucleolus, nucleus, and cytoplasm, chaperoning ribosomal proteins and core histones from the nucleus to the cytoplasm. This protein is also known to sequester the tumor suppressor ARF in the nucleolus, protecting it from degradation until it is needed. Mutations in this gene are associated with acute myeloid leukemia. Dozens of pseudogenes of this gene have been identified.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 33kDa

Observed Molecular Weight: 38kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 4869

SWISS: P06748

Alternate Names: B23; NPM; NPM1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:100 - 1:500 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Protein phosphorylation, Cell Biology Developmental Biology, Cell Cycle, Centrosome.

NCBI Alias: NPM1

Research Use Only