NQO1 Monoclonal Antibody - BT-MCA4131

NQO1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4131-50, BT-MCA4131-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Research Areas: Signal Transduction, Metabolism

Target Protein: NQO1

Applications: WB, IHC, FCM

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4D12

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NQO1

Immunogen: Purified recombinant fragment of human NQO1 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 31kDa

UniProt Accession: P15559

Synonyms: DTD, QR1, DHQU, DIA4, NMOR1, NMORI

GeneID: 1728

Research Use Only