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NRG2 Polyclonal Antibody - E-AB-19325

NRG2 Polyclonal Antibody - E-AB-19325

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NRG2 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-19325-60, E-AB-19325-120, E-AB-19325-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: NRG2

Target Synonym: Divergent of neuregulin 1; Divergent of neuregulin-1; Don 1; DON-1; Neural- and thymus-derived activator for ERBB kinases; Neuregulin 2; Neuregulin-2; NRG-2; Nrg2; NRG2; NTAK; Pro NRG2; Pro-NRG2

Research Areas: Neuroscience, Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: IHC, ELISA

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: O14511

Background: This gene encodes a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the ERBB family of receptors, this protein induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. The products of these genes mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. This gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcript variants encoding distinct isoforms have been described.

Concentration: 1 mg/mL

Immunogen: Synthetic peptide of human NRG2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: IHC 1:50-1:300, ELISA 1:5000-1:10000

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only