Product Description

NSE2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33645-50, RA33645-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: function:E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks. Acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2. SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair., pathway:Protein modification; protein sumoylation., PTM:Sumoylated, possibly via autosumoylation., similarity:Belongs to the NSE2 family., similarity:Contains 1 SP-RING-type zinc finger., subunit:Component of the SMC5-SMC6 complex which consists of SMC5, SMC6, NSMCE2/MMS21 and probably NSMCE1.,

Reactivity: Human, Rat, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 27

Protein Molecular Weight (kDa): 27

Storage: -20°C/1 year

Human Gene ID: 286053

Human SwissProt Number: Q96MF7

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only