Product Description

NTE Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27950-50, RA27950-100

Citations, Manuals and MSDS Available upon request.

Background: patatin like phospholipase domain containing 6 (PNPLA6) Homo sapiens This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Alternative Names: PNPLA6; NTE; Neuropathy target esterase; Patatin-like phospholipase domain-containing protein 6

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 10908

Protein MW (KDa): 150

SWISS: Q8IY17

Source: Rabbit

Research Use Only