Product Description

NTR2 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA27956-50, RA27956-100

Citations, Manuals and MSDS Available upon request.

Background: neurotensin receptor 2 (NTSR2) Homo sapiens The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

Alternative Names: NTSR2; Neurotensin receptor type 2; NT-R-2; NTR2; Levocabastine-sensitive neurotensin receptor

Applications: WB; IHC-p; IF/ICC; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 23620

Protein MW (KDa): 45

SWISS: O95665

Source: Rabbit

Research Use Only