NTRK3 Monoclonal Antibody - BT-MCA4136

NTRK3 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4136-50, BT-MCA4136-100

Citations, Manuals and MSDS Available upon request.

Background: NTRK3 (neurotrophic tyrosine kinase, receptor, type 3), it is a member of the neurotrophic tyrosine receptor kinase (NTRK) family and plays an important role in the development and maintenance of neural tissues. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers.

Research Areas: Neuroscience

Target Protein: NTRK3

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4G5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: NTRK3

Immunogen: Purified recombinant extracellular fragment of human NTRK3 (aa32-429) fused with hIgGFc tag expressed in HEK293 cells.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 94kDa

UniProt Accession: Q16288

Synonyms: TRKC, gp145(trkC)

GeneID: 4916

Research Use Only