Product Description

NUDC3 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES9959-50, ES9959-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The product of this gene functions to maintain the stability of dynein intermediate chain. Depletion of this gene product results in aggregation and degradation of dynein intermediate chain, mislocalization of the dynein complex from kinetochores, spindle microtubules, and spindle poles, and loss of gamma-tubulin from spindle poles. The protein localizes to the Golgi apparatus during interphase, and levels of the protein increase after the G1/S transition. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 30-110

Isotype: IgG

Target: NUDC3

Specificity: NUDC3 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Brain, Epithelium, Pancreas, Placenta,

Observed Band (KD): 39kD

Function: PTM: Phosphorylated upon DNA damage, probably by ATM or ATR
Similarity: Contains 1 CS domain

Subcellular Location: cytoplasm,

Storage and Stability: -20°C/1 year

Gene Name: NUDCD3 KIAA1068

Protein Name: NudC domain-containing protein 3

Mouse SwissProt Number: Q8R1N4

Research Use Only