OAS1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A14623-20, A14623-100
Citations, Manuals and MSDS Available upon request.
Background: This interferon-induced gene encodes a protein that synthesizes 2', 5'-oligoadenylates (2-5As). This protein plays a key role in innate cellular antiviral response, and has been implicated in other cellular processes like cell growth and apoptosis. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection, including SARS-CoV-2, and diabetes mellitus, type 1. This gene is located in a cluster of related genes on chromosome 12.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse, Rat
Protein Weight: 46kDa
Observed Molecular Weight: 46kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 4938
SWISS: P00973
Alternate Names: OIAS; IFI-4; OIASI; IMD100; E18/E16; OAS1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling.
NCBI Alias: OAS1
Research Use Only