OAS2 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA27991-50, RA27991-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: 2'-5'-oligoadenylate synthetase 2 (OAS2) Homo sapiens This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2'-specific nucleotidyl transfer reactions to synthesize 2', 5'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008], Reactivity: Human, Rat, Mouse Host: Rabbit Applications: WB, IHC-p, IF (paraffin section), ELISA Alternate Names: OAS2, 2'-5'-oligoadenylate synthase 2, (2-5')oligo (A) synthase 2, 2-5A synthase 2, p69 OAS / p71 OAS, p69OAS / p71OAS Clonality: Polyclonal Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/20000. Not yet tested in other applications. Molecular Weight: 82 Protein Molecular Weight (kDa): 82 Storage: -20°C/1 year Human Gene ID: 4939 Human SwissProt Number: P29728 Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. Research Use Only