OBSCN Polyclonal Antibody-BS77587

OBSCN Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS77587-50, BS77587-100

Product: 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: Q5VST9

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF/ICC

All Applications: WB,1:500 - 1:2000 | IF/ICC,1:50 - 1:200

Background: The obscurin gene spans more than 150 kb, contains over 80 exons and encodes a protein of approximately 720 kDa. The encoded protein contains 68 Ig domains, 2 fibronectin domains, 1 calcium/calmodulin-binding domain, 1 RhoGEF domain with an associated PH domain, and 2 serine-threonine kinase domains. This protein belongs to the family of giant sacromeric signaling proteins that includes titin and nebulin, and may have a role in the organization of myofibrils during assembly and may mediate interactions between the sarcoplasmic reticulum and myofibrils. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Unmodification

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunofluorescence analysis of U-2 OS cells using OBSCN antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of rat heart using OBSCN antibody at dilution of 1:100. Blue: DAPI for nuclear staining., Immunofluorescence analysis of mouse heart using OBSCN antibody at dilution of 1:100. Blue: DAPI for nuclear staining.

Alternative Name: ARHGEF30; UNC89; OBSCN

Immunogen: Recombinant fusion protein of human OBSCN(NP_443075.3).

Conjugate: Unconjugated

Modification: Unmodified