Occludin Polyclonal Antibody - E-AB-64286

Occludin Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-64286-60, E-AB-64286-120, E-AB-64286-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Occludin

Target Synonym: OCLN; BLCPMG; PPP1R115; PTORCH1; occludin; Occludin

Research Areas: Cancer,Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q16625

Background: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5.

Concentration: 1 mg/mL

Immunogen: Recombinant fusion protein of human Occludin

Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 8kDa/23kDa/31kDa/52kDa/54kDa/59kDa

Observed MW: 62KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only