Product Description

P63-α (3F11) Mouse Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: EM1404-50, EM1404-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: p63 can induce p53-responsive genes and apoptosis, mutation of p63 rarely results in tumors. Research investigators frequently observe amplification of the p63 gene in squamous cell carcinomas of the lung, head and neck. The p63 gene contains an alternative transcription initiation site that yields a 40 kDa δNp63 lacking the transactivation domain, and alternative splicing at the carboxy-terminus yields the α, β, and γ isoforms.

Reactivity: Human, Rat, Mouse

Host: Mouse

Applications: WB, IHC

Clonality: Monoclonal

Immunogen: Synthetic Peptide

Isotype: IgG1

Dilution: WB 1:1,000-2,000   IHC:1, 100-1:200

Concentration: 1mg/mL,

Observed Band (KD): 50-80kDa

Subcellular Location: Nucleus

Storage and Stability: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Research Use Only