PACS1 Polyclonal Antibody - RA33965

PACS1 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA33965-50, RA33965-100 Citations, Manuals and MSDS Available upon request. Background: phosphofurin acidic cluster sorting protein 1 (PACS1) Homo sapiens This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance. [provided by RefSeq, Jul 2008], Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Rat; Mouse GeneID (Human): 55690 Protein MW (KDa): 105 SWISS: Q6VY07 Source: Rabbit Research Use Only