PAI-1/Serpin E1 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A6211-20, A6211-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. The protein also functions as a component of innate antiviral immunity. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.
Category: Polyclonal Antibodies
Applications: WB, IF/ICC, IF-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 45kDa
Observed Molecular Weight: 48kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 5054
SWISS: P05121
Alternate Names: PAI; PAI1; PAI-1; PLANH1; PAI-1/Serpin E1
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IF/ICC, 1:50 - 1:200 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Tumor biomarkers, Signal Transduction, Cell Biology Developmental Biology, Ubiquitin, Endocrine Metabolism, Endocrine and metabolic diseases, Cardiovascular, Angiogenesis, Blood.
NCBI Alias: SERPINE1
Research Use Only