PAK Gamma Monoclonal Antibody - BT-MCA0984

PAK Gamma Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0984-50, BT-MCA0984-100

Citations, Manuals and MSDS Available upon request.

Background: The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell.

Research Areas: Signal transduction; Cancer; Cell biology; Microbiology

Target Protein: PAK2

Applications: WB, IHC-p, IF, ICC, ELISA

Reactivity: Human,Monkey

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Serine,threonine-protein kinase PAK 2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13177; Mouse: Q8CIN4

Synonyms: PAK2; Serine; threonine-protein kinase PAK 2; Gamma-PAK; PAK65; S6; H4 kinase; p21-activated kinase 2; PAK-2; p58

GeneID: Human: 5062

Research Use Only