PAK1/2 (Phospho-Ser199/204) Rabbit Polyclonal Antibody - BT-AP11770

PAK1/2 (Phospho-Ser199/204) Rabbit Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP11770-20, BT-AP11770-50, BT-AP11770-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a family member of serine/threonine p21-activating kinases| known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling| and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Areas: Signal transduction; Cell biology; Cancer

Applications: WB

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: PAK1/2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: Q13153; Mouse: O88643; Rat: P35465

Synonyms: PAK1/2;Ser199/204; Serine/threonine-protein kinase PAK 1; EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK

GeneID: Human: 5058; Rat: 29431

Research Use Only