PAK2 Monoclonal Antibody - BT-MCA3569

PAK2 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3569-50, BT-MCA3569-100

Citations, Manuals and MSDS Available upon request.

Background: PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

Research Areas: Cell Biology

Target Protein: PAK2

Applications: WB, IHC, ICC

Reactivity: Human, Monkey

Clonality: Monoclonal

Clone ID: 3B5

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PAK2

Immunogen: Purified recombinant fragment of PAK2 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): 61kDa

UniProt Accession: Q13177

Synonyms: PAK65, PAKgamma

GeneID: 5062

Research Use Only