Product Description

PAK6 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA33970-50, RA33970-100

Citations, Manuals and MSDS Available upon request.

Background: p21 (RAC1) activated kinase 6 (PAK6) Homo sapiens This gene encodes a member of a family of p21-stimulated serine/threonine protein kinases, which contain an amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. These kinases function in a number of cellular processes, including cytoskeleton rearrangement, apoptosis, and the mitogen-activated protein (MAP) kinase signaling pathway. The protein encoded by this gene interacts with androgen receptor (AR) and translocates to the nucleus, where it is involved in transcriptional regulation. Changes in expression of this gene have been linked to prostate cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 56924

Protein MW (KDa): 74

SWISS: Q9NQU5

Source: Rabbit

Research Use Only