PARP-1 (Acetyl-K521) Polyclonal Antibody - RA28527

PARP-1 (Acetyl-K521) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA28527-50, RA28527-100

Citations, Manuals and MSDS Available upon request.

Background: poly (ADP-ribose) polymerase 1 (PARP1) Homo sapiens This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: wb dilution 1:1000

Alternative Names: Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (NAD (+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1)

Applications: WB; ELISA

Species Cross-Reactivity: Human:K521; Mouse:K520; Rat:K521

GeneID (Human): 142

SWISS: P09874

Source: Rabbit

Research Use Only