Product Description

PARP1 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BZ17041-50, BZ17041-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P09874

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-P, FC

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 FC: 1/50-1/100

Background: Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 113 kDa; Observed MW: 116,24 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of PARP in 293, Jurkat lysates using PARP1 antibody., Western blot analysis of PARP in Hela lysates using PARP antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using PARP1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: PARP1; ADPRT; PPOL; Poly [ADP-ribose] polymerase 1; PARP-1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1

Immunogen: A synthetic peptide of human PARP

Conjugate: Unconjugated

Modification: Unmodified