Product Description

Pax-3 Polyclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: BS6686-50, BS6686-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P23760

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IF

All Applications: WB: 1:500~1:2000
IF: 1:50~1:200

Background: Pax-3 is a protein containing both a paired domain and a paired-type homeodomain. During early neurogenesis, Pax-3 expression is limited to mitotic cells in the ventricular zone of the developing spinal cord and to distinct regions in the hindbrain, midbrain and diencephalon. In 10-12 day embryos, expression of Pax-3 is also seen in neural crest cells of the developing spinal ganglia, the craniofacial mesectoderm and in limb mesenchyme. Mutations in the MITF and Pax-3 genes, encoding transcription factors, are responsible for Waardenburg syndrome II (WSII) and WSI/WSIII, respectively.

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: PAX3 polyclonal antibody detects endogenous levels of PAX3 protein.

Bioworld Molecular Weight: ~ 69 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of Pax-3 polyclonal antibody, Immunofluorescence analysis of MCF7 cells, using Pax-3 polyclonal antibody

Alternative Name: Paired box protein Pax-3; HuP2; PAX3; HUP2

Immunogen: Recombinant full length Human Pax-3.

Conjugate: Unconjugated

Modification: Unmodified