Pax-6 Monoclonal Antibody - BT-MCA0992

Pax-6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA0992-50, BT-MCA0992-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a homeobox and paired domain-containing protein that binds DNA and functions as a regulator of transcription. Activity of this protein is key in the development of neural tissues, particularly the eye. This gene is regulated by multiple enhancers located up to hundreds of kilobases distant from this locus. Mutations in this gene or in the enhancer regions can cause ocular disorders such as aniridia and Peter's anomaly. Use of alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms.

Research Areas: Epigenetics and nuclear signaling; Developmental biology; Stem cells; Neuroscience

Target Protein: PAX6

Applications: WB, FCM, ELISA

Reactivity: Human

Clonality: Monoclonal

Host: Mouse

Isotype: IgG

Full Product Name: Paired box protein Pax-6

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

UniProt Accession: Human: P26367; Mouse: P63015

Synonyms: PAX6; AN2; Paired box protein Pax-6; Aniridia type II protein; Oculorhombin

GeneID: Human: 5080

Research Use Only