PBXIP1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-18751-60, E-AB-18751-120, E-AB-18751-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PBXIP1
Target Synonym: 4732463H20Rik; Hematopoietic PBX interacting protein ; HPIP ; MGC38361; Pre B cell leukemia homeobox interacting protein 1; RP11-307C12.2
Research Areas: Epigenetics and Nuclear Signaling, Signal transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human
Application: IHC, ELISA
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: Q96AQ6
Background: The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.
Concentration: 0.66 mg/mL
Immunogen: Fusion protein of human PBXIP1
Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Purification Method: Antigen affinity purification
Dilution: IHC 1:40-1:200, ELISA 1:5000-1:10000
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only