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PBXIP1 Polyclonal Antibody - E-AB-63905

PBXIP1 Polyclonal Antibody - E-AB-63905

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PBXIP1 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-63905-60, E-AB-63905-120, E-AB-63905-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: PBXIP1

Target Synonym: PBXIP1; HPIP

Research Areas: Epigenetics and Nuclear Signaling, Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q96AQ6

Background: The protein encoded by this gene interacts with the PBX1 homeodomain protein, inhibiting its transcriptional activation potential by preventing its binding to DNA. The encoded protein, which is primarily cytosolic but can shuttle to the nucleus, also can interact with estrogen receptors alpha and beta and promote the proliferation of breast cancer, brain tumors, and lung cancer. Several transcript variants encoding different isoforms have been found for this gene. More variants exist, but their full-length natures have yet to be determined.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human PBXIP1 (NP_065385.2).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:1000-1:2000

Calculated MW: 72kDa/77kDa/80kDa

Observed MW: 110kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only