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PCBP2 Polyclonal Antibody - RA34003

PCBP2 Polyclonal Antibody - RA34003

Regular price $336.00 CAD
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PCBP2 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA34003-50, RA34003-100 Citations, Manuals and MSDS Available upon request. Background: poly (rC) binding protein 2 (PCBP2) Homo sapiens The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly (rC) -binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Storage Instructions: -20°C/1 year Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000 Applications: WB; ELISA Species Cross-Reactivity: Human; Mouse GeneID (Human): 5094 Protein MW (KDa): 40 SWISS: Q15366 Source: Rabbit Research Use Only
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