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Reed Biotech

PCBP2 Polyclonal Antibody - RA34003

PCBP2 Polyclonal Antibody - RA34003

Regular price $360.00 CAD
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PCBP2 Polyclonal Antibody Sizes: 50μL, 100μL Catalogue Numbers: RA34003-50, RA34003-100 Lead times: 1-2 weeks, if manufacturer has product in stock Manufacturer/Ship Location: China Background: poly (rC) binding protein 2 (PCBP2) Homo sapiens The protein encoded by this gene appears to be multifunctional. Along with PCBP-1 and hnRNPK, it is one of the major cellular poly (rC)-binding proteins. The encoded protein contains three K-homologous (KH) domains which may be involved in RNA binding. Together with PCBP-1, this protein also functions as a translational coactivator of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES, promoting poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. The encoded protein is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. This multiexon structural mRNA is thought to be retrotransposed to generate Reactivity: Human, Mouse Host: Rabbit Applications: WB, ELISA Clonality: Polyclonal Dilution: WB 1:500-2000 ELISA 1:5000-20000 Molecular Weight: 40 Protein Molecular Weight (kDa): 40 Storage: -20°C/1 year Human Gene ID: 5094 Human SwissProt Number: Q15366 Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide. Research Use Only
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