PCK1 Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-40269-60, E-AB-40269-120, E-AB-40269-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PCK1
Target Synonym: cytosolic [GTP]; GTP; PCK1; PCKGC; PEP carboxykinase; PEPCK-C; PEPCK1; PEPCKC; Phosphoenolpyruvate carboxykinase 1 (soluble); Phosphoenolpyruvate carboxykinase 1; Phosphoenolpyruvate carboxykinase; Phosphoenolpyruvate carboxykinase; cytosolic [GTP]; Phosphoenolpyruvate carboxykinase; cytosolic; Phosphoenolpyruvate carboxylase; Phosphopyruvate carboxylase
Research Areas: Cancer, Cardiovascular, Metabolism, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Rat
Application: IHC
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P07379
Background: This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.
Concentration: 1 mg/mL
Immunogen: Recombinant Rat Phosphoenolpyruvate carboxykinase, cytosolic [GTP] protein
Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.
Purification Method: Antigen Affinity Purification
Dilution: IHC 1:100-1:200
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only