Product Description

PCNT Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34024-50, RA34024-100

Citations, Manuals and MSDS Available upon request.

Background: pericentrin (PCNT) Homo sapiens The protein encoded by this gene binds to calmodulin and is expressed in the centrosome. It is an integral component of the pericentriolar material (PCM) . The protein contains a series of coiled-coil domains and a highly conserved PCM targeting motif called the PACT domain near its C-terminus. The protein interacts with the microtubule nucleation component gamma-tubulin and is likely important to normal functioning of the centrosomes, cytoskeleton, and cell-cycle progression. Mutations in this gene cause Seckel syndrome-4 and microcephalic osteodysplastic primordial dwarfism type II. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: IHC-p 1:50-300

Applications: IHC-p; IF (paraffin section)

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 5116

Protein MW (KDa): 366

SWISS: O95613

Source: Rabbit

Research Use Only