PD1 Monoclonal Antibody - BT-MCA4285

PD1 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA4285-50, BT-MCA4285-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.

Research Areas: Others

Target Protein: PD1

Applications: WB, FCM

Clonality: Monoclonal

Clone ID: 3B3D9

Host: Mouse

Isotype: Mouse IgG2b

Full Product Name: PD1

Immunogen: Purified recombinant fragment of human PD1 (AA: 192-288) expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Purified antibody in PBS with 0.05% sodium azide

Molecular Weight (Da): 31.6kDa

UniProt Accession: Q15116

Synonyms: PDCD1, PD-1, CD279, SLEB2, hPD-1, hPD-l, hSLE1

GeneID: 5133

Research Use Only