Product Description

PDC6I Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34029-50, RA34029-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: programmed cell death 6 interacting protein (PDCD6IP) Homo sapiens This gene encodes a protein that functions within the ESCRT pathway in the abscission stage of cytokinesis, in intralumenal endosomal vesicle formation, and in enveloped virus budding. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner. This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization, which may be partly responsible for the protection against cell death. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Related pseudogenes have been identified on chromosome 15. [provided by RefSeq, Jan 2012],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Molecular Weight: 95

Protein Molecular Weight (kDa): 95

Storage: -20°C/1 year

Human Gene ID: 10015

Human SwissProt Number: Q8WUM4

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Research Use Only