Product Description

PDE1A Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA34035-50, RA34035-100

Citations, Manuals and MSDS Available upon request.

Background: phosphodiesterase 1A (PDE1A) Homo sapiens Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca (2+) /calmodulin (see CALM1; MIM 114180) -dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca (2+) (Michibata et al., 2001 [PubMed 11342109]; Fidock et al., 2002 [PubMed 11747989]) .[supplied by OMIM, Oct 2009],

Condition: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: WB 1:500-2000 ELISA 1:5000-20000

Applications: WB; ELISA

Species Cross-Reactivity: Human; Mouse

GeneID (Human): 5136

Protein MW (KDa): 58

SWISS: P54750

Source: Rabbit

Research Use Only