PDE4A Polyclonal Antibody
Sizes: 60μL, 120μL, 200μL
Catalogue Numbers: E-AB-92180-60, E-AB-92180-120, E-AB-92180-200
Citations, Manuals and MSDS Available upon request.
Abbreviation: PDE4A
Target Synonym: PDE4; DPDE2; PDE46
Research Areas: Cancer, Signal Transduction
Conjugation: Unconjugated
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Application: WB, IHC, IF
Isotype: IgG
Clonality: Polyclonal
UNIProt ID: P27815
Background: The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Concentration: 1mg/mL
Immunogen: Recombinant fusion protein of human PDE4A
Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.
Purification Method: Affinity purification
Dilution: WB 1:1000-1:2000, IHC 1:50-1:200, IF 1:50-1:200
Calculated MW: 98kD/95kDa/76kDa/72kDa/37kDa/91kDa/96kDa
Observed MW: 80KDa/110KDa
Storage: -20°C/One year. Avoid freeze / thaw cycles.
Shipping: Ice bag
Research Use Only