PDZK1 Rabbit pAb - A5321

PDZK1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A5321-20, A5321-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Category: Polyclonal Antibodies

Applications: WB, ELISA

Cross-reactivity: Mouse

Protein Weight: 57kDa

Observed Molecular Weight: 67kDa

Immunogen: Recombinant protein (or fragment) .

Species: Human

GeneID: 5174

SWISS: Q5T2W1

Alternate Names: CAP70; CLAMP; PDZD1; NHERF3; NHERF-3; PDZK1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Signal Transduction, Endocrine Metabolism.

NCBI Alias: PDZK1

Research Use Only