PEG10 Monoclonal Antibody - BT-MCA3493

PEG10 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Number: BT-MCA3493-50, BT-MCA3493-100

Citations, Manuals and MSDS Available upon request.

Background: PEG10, paternally expressed 10. The PEG10 includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

Research Areas: Epigenetics and nuclear signaling, Stem cells, Cancer

Target Protein: PEG10

Applications: IHC

Reactivity: Human

Clonality: Monoclonal

Clone ID: 4C10A7

Host: Mouse

Isotype: Mouse IgG1

Full Product Name: PEG10

Immunogen: Purified recombinant fragment of human PEG10 expressed in E. Coli.

Storage: 4°C|-20°C for long term storage

Formulation: Ascitic fluid containing 0.03% sodium azide.

Molecular Weight (Da): Isoform RF1 (37kDa)|RF1/RF2 (80kDa)

UniProt Accession: Q86TG7

Synonyms: Edr, HB-1, Mar2, MEF3L, Mart2, RGAG3

GeneID: 23089

Research Use Only